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Botulinum Toxin - 5 Vials x 150 IU
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| |  | | Package: 5 Vials x 150 IU
Usage: Injectable
Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating,etc.
Produced by: China
| | Price: $470.00 |  |
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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online
Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)
DESCRIPTION:
Botulinum Toxin Type A is kind-A toxin that encloses 150 IU in one vial and can be indicated into one patient. Botulinum Toxin Type A is a type of medication to correct light wrinkles and shrink the expression.
BTXA (Botulinum Toxin Type A for Therapy) is a disinfect, lyophilized form of purified botulinum toxin type A, created from the basic toxin of the culture of the Hall strain of Clostridium botulinum developed in a medium containing trypticase and yeast extract. A sequence of cleansing process were extracted to make a clear complex containing of the active high molecular weight toxin protein and an connected hemagglutinin. Once re-diluted and dialyzed the transparent toxin, a precise volume of the sterilized clarified (0.2 microns) toxin were added to a solution containing gelatin-dextran-sucrose, and then lyophilized. Each vial of BTXA has 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.
INDICATIONS:
This medication is administrated for the cure of blepharospasm, hemi facial tremor in adults and some categories of strabismus, especially for serious paralytic strabismus, comitant strabismus, strabismus provoked by endocrine myopathy also strabismus which cannot be fixed through operation. Anti-Wrinkle, Thin expressions and legs.
USAGE AND DOSAGE:
1. Position for injection:
- For blepharospasm: the injection must be injected intramuscularly at several points of superior and inferior tops, i.e., using 4 to 5 places of insertion into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial spasm: besides the points mentioned above, three other locations on middle, lower face and cheek have to be inserted intramuscularly. BTXA may be used at the points of two sides of eyebrow, upper lip or the lower jaw agreeing to the diseases.
- For strabismus: the BTXA is inoculated using a coaxial electrode syringe with electromyography direction or amplifier under topical anesthesia of 0.5% Decarine. The inoculations into extra ocular muscles are selected agreeing to the variety and lacation of strabismus.
2. Dose:
150 IU must be watering into 2.0-2.5ml sterilized water before injecting.
Melt with sterile normal saline according to diverse requests before inserting. The white loose product changes to be monochrome or yellowish translucent solution after the thinning.
- For blepharopasm also hemi facial spasm: the injection could be suggested following above guidelines. The initial dose of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. In case the initial cure is considered deficient 1 week later, an extra injection may be suggested. Dual dose of 5 U / 0.1 ml may be given to recrudescent patients. But the limitation of complete dose of 55 U for 1 inoculation and 200 U for 1 month should not be exceeded.
- For strabismus: for vertical as well horizontal muscle strabismus of less than 20 prism diopters, the primary dosing into every muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the first dosing into every muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the primary dosage into every muscle is 2.5 U as well may be increase (to 5.0 every) depending on the response; for insistent VI cranial nerve paralysis lasted for more than one month. The injecting volume into ever muscle must not more 0.1 ml. To persons, having insufficient response, extra injection can be indicated. To recrudescent people, the measure can be repeated or increased irregularly. But for each muscle the extreme dose should be less than 5 U / inj.
The Dilution of BTXA:
The dissolving of this product with sterilized normal saline has to be done carefully on the basis of real request. Following is a reference table of watering to be recommended. The vial should be trembling smoothly once adding sterile normal saline to the complete thinning. The thinning BTXA (Botulinum Toxin Type A for Therapy) has to be administrated at once or stored in refrigerator at 2-8 degrees and to be injected within 4 hours. The ampule and the syringe used with this product also the lasting BTXA solution has to be disposed after sterilization.
UNWANTED RESULTS:
Short-term ptosis of the eyelid, drawback of the inferior eyelid, minimized blinking, eyelid close moderately, weakness of face muscles, etc. can happen to a few patients who inject this preparation remedy for blepharospasm and hemi facial contraction. However, all the symptoms will vanish without any healing within three to eight weeks. Passing and different degree of ptosis of the eyelid, vertical deviancy also seldom mydriasis, which connected to the distribution of the toxin to the muscles nearby, may happen to some people who used BTXA (Botulinum Toxin Type A for Therapy) treatment for strabismus. The indications will vanish without any therapy within a few weeks.
CONTRAINDICATIONS:
This medication is not recommended in patients with anaphylactic constitution and identified sensitivity to this product.
WARNINGS:
The injection technique must be administrated later to persons who have temperature, grave infectious illness and prudently to the individuals with heart, liver, lung illness, active tuberculosis, blood malady also pregnant women.
Botulinum toxin can be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of medications must not be taken during the inserting of BTXA (Botulinum Toxin Type A for Therapy).
BTXA (Botulinum Toxin Type A for Therapy) is in low effect or without any effect to the individuals in the next situations: strabismus above 50 prism diopters, fixed strabismus, strabismus caused by excessively modified surgery, chronic paralysis strabismus, also chronic VI or III cranial nerve paralysis, severe muscle fiber contracture.
1:1000 adrenalines have to be prepared in case of occasional accident.
EXPIRATION:
Three years from the day of lyophilization. The effect is clear and can be last 6 months.
STORE:
Store at a temperature of -5 to -20 gr C (23 to -4 gr F). Store new vial at -5 temperatures.
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