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Botulinum Toxin - 10 Vials x 150 IU
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| |  | | Package: 5 Vials x 150 IU
Usage: Injectable
Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating, etc.
Produced by: China
| | Price: $880.00 |  |
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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online
Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)
DESCRIPTION:
Botulinum Toxin Type A is kind-A toxin that encloses 150 IU in one vial and may be used into one patient. Botulinum Toxin Type A is a kind of product to correct small folds and shrink the expression.
This injection is a hygienic, lyophilized formula of cleansed botulinum toxin type A, made from the crude toxin of the culture of the Hall strain of Clostridium botulinum developed in a medium having trypticase also yeast extract. A series of purifying method were used to make a crystal clear complex consisting of the active high molecular weight toxin protein and an linked hemagglutinin. Once re-dissolved and dialyzed the crystal-like toxin, a correct amount of the disinfected cleaned (0.2 microns) toxin were added to a solution holding gelatin-dextran-sucrose, and then lyophilized. Every vial of BTXA contains 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.
INDICATIONS:
This medication is administrated for the treatment of blepharospasm, hemi facial tremor in adults and some categories of strabismus, specialy for important paralytic strabismus, comitant strabismus, strabismus instigated by endocrine myopathy also strabismus which cannot be modified through operation. Anti-Wrinkle, Thin faces and legs.
USAGE AND DOSING:
1. Place for inoculation:
- For blepharospasm: the injection has to be taken intramuscularly at number of points of superior also inferior lids, i.e., taking 4 to 5 points of insertion into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial tremor: besides the locations mentioned above, three other locations on middle, lower face also cheek should be inserted intramuscularly. BTXA can be injected at the places of two parts of eyebrow, upper lip or the lower jaw agreeing to the sicknesses.
- For strabismus: the BTXA is injected using a coaxial electrode syringe with electromyography direction or amplifier under topical anesthesia of 0.5% Decarine. The injections into extra ocular muscles are selected according to the variety as well place of strabismus.
2. Measuring:
150 IU must be dissolved into 2.0-2.5ml sterilized water before inoculating.
Thin with sterile normal saline agreeing to different needs before inserting. The white loose product changes to be neutral or yellowish translucent solution after the diluted.
- For blepharopasm also hemi facial tremor: the injection could be indicated following above directions. The primary measure of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. In case the first cure is considered insufficient 1 week later, a supplementary insertion could be suggested. Dual dose of 5 U / 0.1 ml may be indicated to recrudescent individuals. But the limitation of complete dose of 55 U for 1 insertion and 200 U for one month must not be exceeded.
- For strabismus: for vertical as well horizontal muscle strabismus of less than 20 prism diopters, the initial dose into every muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the initial dose into every muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the first dosage into each muscle is 2.5 U also could be rised (to 5.0 each time) depending on the reaction; for persistent VI cranial nerve paralysis continued for more than one month. The inoculating volume into ever muscle must not exceed 0.1 ml. To patients, having insufficient reaction, supplementary inoculation can be indicated. To recrudescent persons, the dosage can be repeated or increased irregularly. But for each muscle the maximum measure must be less than 5 U / inj.
The Thinning of BTXA (Botulinum Toxin Type A for Therapy):
The watering of BTXA (Botulinum Toxin Type A for Therapy) with sterile normal saline must be prepared carefully on the basis of real needs. Following is a reference table of watering to be mentioned. The vial must be trembling mildly after adding sterile normal saline to the whole thinning. The dilution BTXA must be injected at once or maintained in ice-box at 2 to 8 degrees and to be injected within 4 hours. The ampule as well as the syringe used with this product as well as the lasting BTXA solution has to be prepared after disinfection.
UNDESIRABLE EFFECTS:
Short-term ptosis of the eyelid, problem of the lower eyelid, minimized blinking, eyelid close in part, softness of facial muscles, etc. may happen to a number of individuals who received this medication remedy for blepharospasm also hemi facial tremor. But, all the indications will vanish without any treatment within three to 8 weeks. Temporary and dissimilar degree of ptosis of the eyelid, vertical deviance also seldom mydriasis, which related to the dispersion of the toxin to the muscles adjacent, can happen to some patients who used this injection remedy for strabismus. The signs will go without any remedy within a few weeks.
CONTRAINDICATIONS:
This injection is not suggested in individuals with anaphylactic parts as well known sensitivity to this medication.
ADMONITIONS:
The inoculation method has to be suggested later to individuals who have temperature, severe infectious malady and prudently to the people with heart, liver, lung troubles, active tuberculosis, blood illness also pregnant women.
Botulinum toxin may be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of products should not be used during the using of BTXA.
BTXA (Botulinum Toxin Type A for Therapy) is in low reaction or without any result to the persons in the next situations: strabismus above 50 prism diopters, fixed strabismus, strabismus caused by excessively corrected surgery, chronic paralysis strabismus, also chronic VI or III cranial nerve paralysis, serious muscle fiber contracture.
1:1000 adrenalines should be set in case of occasional accident.
EXPIRATION:
3 years from the day of lyophilization. The result is obvious and can be last six months.
STORE:
Store at a temperature of -5 to -20 gr C (23 to -4 gr F). Keep new vial at -5 temperatures.
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