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Botulinum Toxin - 1 Vial x 150 IU
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| |  | | Package: 1 Vial x 150 IU
Usage: Injectable
Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating,etc.
Produced by: China
| | Price: $145.00 |  |
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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online
Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)
DESCRIPTION:
Botulinum Toxin Type A is type-A toxin which encloses 150 IU in one vial and may be indicated into one man. Botulinum Toxin Type A is a category of preparation to correct light wrinkles as well as shrink the face.
BTXA (Botulinum Toxin Type A for Therapy) is a disinfect, lyophilized form of cleaned botulinum toxin type A, produced from the unfinished toxin of the culture of the Hall strain of Clostridium botulinum grown in a medium containing trypticase as well yeast extract. A sequence of purifying procedure were used to form a crystalline complex consisting of the active high molecular weight toxin protein as well as an related hemagglutinin. Once re-dissolved and dialyzed the crystalline toxin, a precise amount of the sterile filtered (0.2 microns) toxin were added to a solution holding gelatin-dextran-sucrose, and then lyophilized. Each vial of BTXA has 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.
INDICATIONS:
This product is administrated for the treatment of blepharospasm, hemi facial contraction in grown-ups also some varienties of strabismus, specialy for serious paralytic strabismus, comitant strabismus, strabismus caused by endocrine myopathy and strabismus which cannot be corrected with surgery. Anti-Wrinkle, Thin expressions and legs.
USAGE AND DOSING:
1. Place for insertion:
- For blepharospasm: the injection should be taken intramuscularly at several points of upper also inferior covers, i.e., taking 4 to 5 places of injection into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial tremor: besides the locations mentioned above, three other points on middle, lower face and cheek have to be inserted intramuscularly. BTXA may be injected at the places of two sides of eyebrow, upper lip or the lower jaw according to the diseases.
- For strabismus: the BTXA (Botulinum Toxin Type A for Therapy) is inoculated using a coaxial electrode syringe with electromyography supervision or amplifier under topical anesthesia of 0.5% Decarine. The insertions into additional ocular muscles are selected agreeing to the form also place of strabismus.
2. Dosage:
150 IU must be diluting into 2.0-2.5ml sterilized water before inoculating.
Melt with sterile normal saline agreeing to different requirements before administrating. The white loose product changes to be colorless or yellowish transparent solution after the dissolved.
- For blepharopasm and hemi facial tremor: the injection may be prescribed following above advices. The primary measure of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. If the primary dealing is considered deficient one week later, an additional inoculation may be suggested. Dual measure of 5 U / 0.1 ml may be given to recrudescent people. But the limitation of entire dosage of 55 U for one insertion and 200 U for 1 month must not be overdone.
- For strabismus: for vertical as well horizontal muscle strabismus of less than 20 prism diopters, the primary dosing into every muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the initial dosage into each muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the first measure into every muscle is 2.5 U and can be increase (to 5.0 each time) depending on the reply; for insistent VI cranial nerve paralysis continued for more than one month. The inoculating volume into each muscle should not more 0.1 ml. To people, taking insufficient reaction, extra insertion could be suggested. To recrudescent persons, the dose can be repeated or increased irregularly. But for each muscle the extreme measure has to be less than 5 U / inj.
The Dilution of BTXA (Botulinum Toxin Type A for Therapy):
The dilution of this injection with sterilized normal saline should be done carefully on the basis of real necessities. Succeding is a reference table of dilution to be recommended. The vial has to be trembling smoothly after adding sterile normal saline to the complete dissolving. The watering BTXA has to be injected at once or kept in refrigerator at 2 to 8 degrees as well to be used within 4 hours. The vessel as well as the needle used with this medication as well as the residual BTXA solution must be prepared after cleansing.
NEGATIVE FEEDBACKS:
Momentary ptosis of the eyelid, disadvantage of the minor eyelid, reduced blinking, eyelid close in part, softness of facial muscles, etc. can arise to a number of persons who take this medication treatment for blepharospasm as well hemi facial shudder. But, all the signs will go without any cure within 3 to 8 weeks. Momentary also different degree of ptosis of the eyelid, vertical deviance as well seldom mydriasis, which related to the distribution of the toxin to the muscles adjacent, may happen to some people who received BTXA therapy for strabismus. The signs will disappear without any cure within a few weeks.
CONTRAINDICATIONS:
BTXA is not indicated in people with anaphylactic parts as well recognized reaction to any ingredient.
PRECAUTIONS:
The insertion method must be suggested later to individuals who have fever, severe infectious malady also carefully to the individuals with heart, liver, lung troubles, active tuberculosis, blood diseases also pregnant women.
Botulinum toxin could be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of products must not be taken during the injecting of BTXA (Botulinum Toxin Type A for Therapy).
BTXA (Botulinum Toxin Type A for Therapy) is in low result or without any reaction to the persons in the next situations: strabismus above 50 prism diopters, fixed strabismus, strabismus provoked by extremely modified surgery, chronic paralysis strabismus, also chronic VI or III cranial nerve paralysis, grave muscle fiber contracture.
1:1000 adrenalines must be set in case of occasional accident.
SHELF LIFE:
3 years from the date of lyophilization. The effect is obvious and may be last 6 months.
STORING:
Keep at a temperature of -5 to -20 gr C (23 to -4 gr F). Keep unused vial at -5 temperatures.
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